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Liverpool will once again be searching for a Champions League lifeline as PSV Eindhoven visit Anfield on Wednesday for Matchday 5 of the league phase.
After a turbulent stretch domestically, Arne Slot’s men have found relief in Europe, claiming morale-boosting victories over Eintracht Frankfurt and Real Madrid. Those results have softened the blow of a Premier League title defence that has completely unraveled.
Saturday’s 3-0 defeat to Nottingham Forest marked Liverpool’s sixth loss in 12 league games, a stark contrast to last season’s title-winning run, where they suffered only four defeats across the entire campaign. Questions continue to swirl around record-breaking signings Florian Wirtz and Alexander Isak, the two most expensive players in British football history, both yet to find their stride.
Projected Liverpool Lineup vs. PSV
Formation: 4-3-3
Alisson (GK)
Szoboszlai, Konaté, Van Dijk, Robertson
Jones, Gravenberch, Mac Allister
Salah, Ekitike, Gakpo
Liverpool Team News
Slot will make a late fitness call on Florian Wirtz, who missed the Forest match due to a muscular issue. His return would be invaluable, especially as Dominik Szoboszlai is expected to fill in at right-back again with both Jeremie Frimpong and Conor Bradley still unavailable. Of the pair, Frimpong has the best chance of a late inclusion.
Andy Robertson is expected to reclaim his spot at left-back, while Slot may opt to start Hugo Ekitike over the struggling Alexander Isak up front.
Liverpool Injury Report
Conor Bradley
Injury: Muscle
Return: December 13
Slot confirmed Bradley picked up the injury during the November international break and will be out for “22 days.” The home match vs. Brighton looks the earliest return.
Florian Wirtz
Injury: Muscle
Return: November 30
Wirtz’s injury is considered less severe. Slot believes he could be ready for the weekend clash against West Ham.
Jeremie Frimpong
Injury: Hamstring
Return: November 26
This marks his second hamstring issue since joining Liverpool. Slot says facing Forest was unlikely, but Wednesday’s PSV match remains possible.
Giovanni Leoni
Injury: Anterior cruciate ligament ACL tear
Return:August 2026
A devastating debut saw the summer signing rupture his ACL vs. Southampton. He underwent immediate surgery and is ruled out for the season.
Liverpool vs. PSV – Match Details
- Date: Wednesday, November 26, 2025
- Kickoff: 8 p.m. local / 3 p.m. ET / 12 p.m. PT / 7 a.m. AEDT (Nov. 27)
- Venue: Anfield, Liverpool (UK)
- Competition: UEFA Champions League – League Phase, Matchweek 5
- Referee: Alejandro Hernandez
- VAR: Guillermo Cuadra Fernandez
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